Reference Library

We welcome you to explore our library of references and publications. If you have questions or need additional information on any of FzioMed’s products, please contact us.

Core Science

    • A modern biomaterial for adhesion prevention.
      diZerega et al. J Biomed Mater Res B Appl Biomater; Apr 1(1):239-50, 2007.
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    • Evaluation of FzioMed adhesion barrier gel on dural healing in a model of epidural fibrosis in rabbits.
      Rodgers KE, et al. Poster. Congress of Neurological Surgeons (CNS), Denver, CO USA, 2003.
    • Reduction of epidural fibrosis in lumbar surgery with Oxiplex adhesion barriers of carboxymethylcellulose and polyethylene oxide.
      Rodgers KE, et al. Spine J, 3:277-284, 2003.
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    • Improving flexor tendon gliding by using the combination of carboxymethylcellulose polyethylene oxide on murine model
      By: Andreea Mioara Corduneanu-Luca, et al.

Spine Surgery

      • Reduction of Leg Pain by Oxiplex Gel After Lumbar Discectomy in Patients With Predominant Leg Pain and Elevated Levels of Lower Back Pain – A Prospective, Randomized, Blinded, Multicenter Clinical Study.
        Wei Lei, MD,* Ronald J. Ehmsen, ScD,w Richard P. Chiacchierini, PhD,zJohn L. Krelle, MBA,w and Gere S. diZerega, MDy
      • Clinical assessment of a CMC/PEO gel to inhibit postoperative epidural adhesion formation after lumbar discectomy: a randomized, control study.
        Liu et al. Arch Orthop Trauma Surg; 133:295-301, 2013
      • Oxiplex reduces leg pain, back pain, and associated symptoms after lumbar discectomy.
        Spine (Phila Pa 1976). 2012 Apr 15;37(8):631-41
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      • Use of temporary implantable biomaterials to reduce leg pain and back pain in patients with sciatica and lumbar disc herniation.
        diZerega et al. Materials; 3:3331-3368, 2010. (Open Access Article)
      • Oxiplex reduces the incidence of back pain, leg pain and associated symptoms 6 months following single level lumbar laminectomy for removal of herniated disc.
        Wang, Arnold & Oxiplex Study Group. Abstract. North American Spine Society (NASS) 2008.
      • Multicenter study evaluating Oxiplex in lumbar surgery.
        Kim, Arnold & Oxiplex Study Group. Abstract. Congress of Neurological Surgeons (CNS) 2008.
      • Use of Carboxymethylcellulose / Polyethylene Oxide Gel in Microdiscectomy With lnterlaminectomy: A Case Series Comparison With Long-term Follow-up.
        Assietti R, Mora A, Brayda-Bruno M. Spine 33(16):1762-1765, 2008.
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      • Oxiplex reduces the incidence of back pain, leg pain and associated symptoms 6 months following single-level lower lumbar surgery for removal of herniated disc.
        Blumenthal S, et al. Poster presentation, Geneva, Switzerland, SpineWeek 2008.
      • Oxiplex intraoperative gel: an adjuvant to lumbar disc surgery for the reduction of post-surgical pain.
        Blumenthal & Oxiplex Study Group. Abstract. Spine Arthroplasty Society(SAS) 2008.
      • Oxiplex gel reduces neurological sequelae following lumbar surgery.
        Arnold & Oxiplex Study Group.  Annual Meeting of the American Association of Neurological Surgeons (AANS), Chicago, 2008.
      • Safety of carboxymethylcellulose / polyethylene oxide for the prevention of adhesions in lumbar disc herniation – consecutive case series review.
        Fransen et al. Annals of Surgical Innovation and Research; 2(2) 2008.
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      • Use of novel gel-formulated anti-adhesion barrier for prevention of fibrotic adhesions in lumbar micro-discectomy procedures.
        Guizzardi R, Morichi R, Vagaggini A, Pandolfo C, Giordano GP. Abstract. Congress of Neurological Surgeons (CNS), October 2006.
      • Reduction in leg pain and lower extremity weakness with Oxiplex/SP gel for 1 year after laminectomy, laminotomy and discectomy.
        Kim et al. Neurosurg Focus 17(1): Clinical Pearl 1, 2004.
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      • Reduction of radiculopathy and pain with Oxiplex/SP gel after laminectomy, laminotomy, and discectomy: a pilot clinical study.
        Kim et al. Spine 15;28(10):1080-7; discussion 1087-8, May 15 2003
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      • MRI image of Oxiplex at 10 days post-op.
      • The Lumbar Spine Outcomes Questionnaire: its development and psychometric properties.
        BenDebba et al. Spine J. 2007 Jan-Feb;7(1):118-32.
      • NASS Abstract

Hand Surgery

      • Efficacy and Safety of Dynavisc gel in Prevention of Scar Adhesions Recurrence After Flexor Tendons Tenolysis in Zone 2.
        Ann. Ital. Chir., 2023, 5: 529-536 pii: S0003469X23039180
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      • Prevention of Peritendinous Adhesions after Tenolysis by means of a CarboxyMethylcellulose (CMC), Poly-Ethylene Oxide (PEO) Based Gel: A Light and Electron Microscope Study in the Rabbit.
        Riccio M. To be published in Hand Surgery
      • The use of Dynavisc(R) in Shoulder Surgery to prevent shoulder stiffness.
        Magobotha S. Scheduled for the FzioMed Satallite Symposium at FESSH 2015.
      • Dynavisc Anti Adhesion Gel in Neurolysis.
        Battiston B. Presented at FESSH 2014 Paris.
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      • Preliminary report on a new adhesion gel barrier (Dynavisc®) in Hand Surgery.
        Di Giuseppe P. Presented at FESSH; Antwerp 2012 & Antalya 2013

Peritoneal Surgery

      • Oxiplex/AP Brochure
      • Oxiplex/AP 2 Page Brochure
      • Oxiplex/AP for Intrauterine Use
      • Lundorff et al. Clinical evaluation of a viscoelastic gel for reduction of adhesions following gynaecological surgery by laparoscopy in Europe. Hum Reprod. 2005 Feb;20(2):514-20.Epub 2004 Dec 9
      • Young et al. Reduction of postoperative adhesions after laparoscopic gynecological surgery with Oxiplex/AP Gel: a pilot study. Fertil Steril.2005 Nov;84(5):1450-6
      • Clinical Evaluation of Endometriosis and Differential response to Surgical Therapy with and without Application of Oxiplex AP Adhesion Barrier Gel
        By: Gere S. diZerega, M.D., James Coad, M.D., and Jacques Donnez, M.D.
      • Oxiplex/AP Animation
      • Oxiplex/AP Application to Ovary
      • Oxiplex/AP Application to Pelvic Sidewall

Intrauterine Surgery

    • Di Spiezio Sardo et al. Efficacy of a polyethylene oxide-sodium carboxymethylcellulose gel in prevention of intrauterine adhesions after hysteroscopic surgery. JMIG.2011.Apr;18(4):462-9
    • Di Spiezio Sardo et al. Hysteroscopic outpatient metroplasty to expand dysmorphic uteri (HOME-DU technique): a pilot study. Reproductive BioMedicine Online. 2014

Last Updated: May 3, 2024